SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro” by Hui Jang and Ya-Fang Mei says on page 8: “Our findings provide evidence of the spike protein hijacking the DNA damage repair machinery and adaptive immune machinery in vitro.“. (1)

Folks were warning from the beginning that about negative effects upon TP53.

“Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.” (1)

1. Jiang, Hui, and Ya-Fang Mei. “SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro.” Viruses, vol. 13, no. 10, Oct. 2021, p. 2056. PubMed Central, https://doi.org/10.3390/v13102056 and https://pmc.ncbi.nlm.nih.gov/articles/PMC8538446/.